A comparison of descriptive variables for clinical patients and symptomatic volunteers with depressive disorders

被引:25
作者
Rapaport, MH
Zisook, S
Frevert, T
Seymour, S
Kelsoe, JR
Judd, LL
机构
[1] SAN DIEGO VET AFFAIRS MED CTR,PSYCHIAT SERV,LA JOLLA,CA
[2] FINCH UNIV HLTH SCI CHICAGO MED SCH,CHICAGO,IL
关键词
D O I
10.1097/00004714-199606000-00009
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Uncertainty about the generalizability of results from clinical trials is a nagging issue plaguing psychiatric research. The possible bias introduced by the use of subjects recruited from advertisements is one source of concern. Investigators question whether these subjects are representative of the types of individuals who seek treatment in clinical practice. This article compares and contrasts demographic characteristics, functional disabilities, symptomatologies, and the health beliefs and expectations of a cohort seeking treatment at a university outpatient clinic with a, cohort of symptomatic volunteers recruited by advertisements. These two groups mere alike in most variables; however, the clinical subjects reported more recent exposure to psychotropic medications and were more Likely to indicate that they wanted psychotherapy. The symptomatic volunteers were slightly older, endorsed more psychiatric symptoms, drank more alcohol, and believed that combined pharmacology and psychotherapy would most help them. These findings suggest that the two cohorts were remarkably similar on most variables.
引用
收藏
页码:242 / 246
页数:5
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