Mechanisms of respiratory innervation during embryonic development

被引：34

作者：

Aven, Linh ^{[1
]}

Ai, Xingbin ^{[1
]}

机构：

[1] Boston Univ, Sch Med, Ctr Pulm, Boston, MA 02118 USA

来源：

ORGANOGENESIS | 2013年 / 9卷 / 03期

关键词：

respiratory tract; brain-derived neurotrophic factor; intrinsic neuron; extrinsic neuron; neurotrophin; glial cell-derived neurotrophic factor; lung development; AIRWAY SMOOTH-MUSCLE; MICE LACKING GDNF; ENTERIC NERVOUS-SYSTEM; NEURAL CREST CELLS; NEUROEPITHELIAL BODIES; INTRINSIC INNERVATION; AFFERENT-PROJECTIONS; LUNG DEVELOPMENT; FETAL LUNG; NEURONS;

D O I：

10.4161/org.24842

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

070307 [化学生物学]; 071010 [生物化学与分子生物学];

摘要：

During embryogenesis, the development of the respiratory tract is closely associated with the formation of an extensive neuronal network. While the topic of respiratory innervation is not new, and similar articles were published previously, recent studies using animal models and genetic tools are breathing new life into the field. In this review, we focus on signaling mechanisms that underlie innervation of the embryonic respiratory tract.

引用

页码：194 / 198

页数：5

共 52 条

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Pulmonary intraepithelial vagal nodose afferent nerve terminals are confined to neuroepithelial bodies: an anterograde tracing and confocal microscopy study in adult rats [J].