Activity of moxifloxacin against mycobacteria

被引：113

作者：

Gillespie, SH ^{[1
]}

Billington, O ^{[1
]}

机构：

[1] UCL Royal Free & Univ Med Sch, Dept Med Microbiol, London NW3 2PF, England

来源：

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 1999年 / 44卷 / 03期

关键词：

D O I：

10.1093/jac/44.3.393

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Moxifloxacin is an 8-methoxyquinolone compound with activity against a wide range of bacteria. We tested its activity in comparison with four other quinolones and isoniazid against clinical isolates of mycobacteria. It proved to be the most active of the quinolones tested against Mycobacterium tuberculosis (MIC90 0.25 mg/L), Mycobacterium avium-intracellulare (MIC90 1.0 mg/L), Mycobacterium kansasii (MIC90 0.06 mg/L) and Mycobacterium fortuitum (MIC90 1 mg/L). These data indicate that moxifloxacin merits further study as an antimycobacterial agent.

引用

页码：393 / 395

页数：3

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