Resistance is futile: Assimilation of cellular machinery by HIV-1

被引:34
作者
Perez, OD
Nolan, GP [1 ]
机构
[1] Stanford Sch Med, Dept Microbiol & Immunol, Stanford, CA 94305 USA
[2] Stanford Sch Med, Dept Mol Pharmacol, Stanford, CA 94305 USA
关键词
D O I
10.1016/S1074-7613(01)00238-2
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
HIV-1 budding appears to require Vps4 and Tsg101-two proteins that have links to endosomal sorting machinery. A picture emerges wherein divergent viruses recruit endosomal proteins like Tsg101 to gain access to ubiquitin processes that play a crucial role during viral budding.
引用
收藏
页码:687 / 690
页数:4
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