The role of specific binding in human serum albumin adsorption to self-assembled monolayers

被引：28

作者：

Choi, EJ ^{[1
]}

Foster, MD ^{[1
]}

机构：

[1] Univ Akron, Maurice Morton Inst Polymer Sci, Akron, OH 44325 USA

来源：

LANGMUIR | 2002年 / 18卷 / 02期

关键词：

D O I：

10.1021/la010964j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The role of specific binding in human serum albumin (HSA) adsorption to self-assembled monolayers (SAM) was studied using X-ray reflectometry. HSA is the most abundant protein in human blood and it has several strong hydrophobic binding sites for fatty acid molecules. It was found that when the binding pockets of HSA are empty, it binds more tenaciously to a loosely packed SAM than to a densely packed SAM.

引用

页码：557 / 561

页数：5

共 32 条

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