Reversible assembling of microfluidic devices by aspiration

被引:24
作者
Le Berre, M.
Crozatier, C.
Casquillas, G. Velve
Chen, Y.
机构
[1] Ecole Normale Super, F-75005 Paris, France
[2] CNRS, Lab Photon & Nanostruct, F-91460 Marcoussis, France
关键词
microfluidics; aspiration; surface functionalization; assembling method;
D O I
10.1016/j.mee.2006.01.257
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
This paper deals with a novel and flexible method for microfluidic device assembling. In general, microfluidic device assembly is obtained by irreversible sealing with anodic, thermal or chemical bonding. Reversible assembly can be obtained by aspiration through a crossing channel network (CCN) between the two pieces of microfluidic device (channels and substrate). In this way, relatively high injection pressure can be achieved in microfluidic channels without leakage. We describe the principle and the fabrication of such PDMS devices and also show two examples of the described assembly method applied to surface functionalization. (c) 2006 Elsevier B.V. All rights reserved.
引用
收藏
页码:1284 / 1287
页数:4
相关论文
共 14 条
[1]   SILICON FUSION BONDING FOR FABRICATION OF SENSORS, ACTUATORS AND MICROSTRUCTURES [J].
BARTH, PW .
SENSORS AND ACTUATORS A-PHYSICAL, 1990, 23 (1-3) :919-926
[2]  
Bernard A, 2000, ADV MATER, V12, P1067, DOI 10.1002/1521-4095(200007)12:14<1067::AID-ADMA1067>3.0.CO
[3]  
2-M
[4]  
CROZATIER C, IN PRESS MICROELECTR
[5]   Patterned delivery of immunoglobulins to surfaces using microfluidic networks [J].
Delamarche, E ;
Bernard, A ;
Schmid, H ;
Michel, B ;
Biebuyck, H .
SCIENCE, 1997, 276 (5313) :779-781
[6]   Topographical Patterning of Chemically Sensitive Biological Materials Using a Polymer-Based Dry Lift Off [J].
Ilic, B. ;
Craighead, H. G. .
BIOMEDICAL MICRODEVICES, 2000, 2 (04) :317-322
[7]   A general method for patterning gradients of biomolecules on surfaces using microfluidic networks [J].
Jiang, XY ;
Xu, QB ;
Dertinger, SKW ;
Stroock, AD ;
Fu, TM ;
Whitesides, GM .
ANALYTICAL CHEMISTRY, 2005, 77 (08) :2338-2347
[8]  
KO WH, 1985, BONDING TECHNIQUES M, P41
[9]  
LEBERRE M, UNPUB
[10]   Poly(dimethylsiloxane) as a material for fabricating microfluidic devices [J].
McDonald, JC ;
Whitesides, GM .
ACCOUNTS OF CHEMICAL RESEARCH, 2002, 35 (07) :491-499