Renaissance of the hygiene hypothesis

被引：60

作者：

Liu, Andrew H.

Leung, Donald Y. M.

机构：

[1] Natl Jewish Med & Res Ctr, Div Pediat Allergy & Immunol, Denver, CO 80206 USA

[2] Univ Colorado, Sch Med, Dept Pediat, Boulder, CO 80309 USA

来源：

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY | 2006年 / 117卷 / 05期

关键词：

hygiene; endotoxin; toll-like receptor; asthma; allergy; atopic dermatitis; allergic rhinitis; atopy; microbes; injection;

D O I：

10.1016/j.jaci.2006.03.027

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

引用

页码：1063 / 1066

页数：4

共 38 条

[1] Cutting edge: Different toll-like receptor agonists instruct dendritic cells to induce distinct th responses via differential modulation of extracellular signal-regulated kinase-mitogen-activated protein kinase and c-fos [J].

Agrawal, S ;

Agrawal, A ;

Doughty, B ;

Gerwitz, A ;

Blenis, J ;

Van Dyke, T ;

Pulendran, B .

JOURNAL OF IMMUNOLOGY, 2003, 171 (10) :4984-4989

[2] Prenatal lipopolysaccharide-exposure prevents allergic sensitization and airway inflammation, but not airway responsiveness in a murine model of experimental asthma [J].

Blümer, N ;

Herz, U ;

Wegmann, M ;

Renz, H .

CLINICAL AND EXPERIMENTAL ALLERGY, 2005, 35 (03) :397-402

[3] Environmental exposure to endotoxin and its relation to asthma in school-age children [J].

Braun-Fahrländer, C ;

Riedler, J ;

Herz, U ;

Eder, W ;

Waser, M ;

Grize, L ;

Maisch, S ;

Carr, D ;

Gerlach, F ;

Bufe, A ;

Lauener, RP ;

Schierl, R ;

Renz, H ;

Nowak, D ;

von Mutius, E .

NEW ENGLAND JOURNAL OF MEDICINE, 2002, 347 (12) :869-877

[4] Conjugation of 3′ hexameric deoxyriboguanosine run to phosphodiester CpG oligodeoxynucleotides can inhibit allergenspecific 19E synthesis with less risk of splenornegaly [J].

Chang, YS ;

Kim, YK ;

Min, KU ;

Kim, YY ;

Seong, YC ;

Cho, SH .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2005, 116 (06) :1388-1390

[5] Airway peptidoglycan and immunostimulatory DNA exposures have divergent effects on the development of airway allergen hypersensitivities [J].

Chisholm, D ;

Libet, L ;

Hayashi, T ;

Horner, AA .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2004, 113 (03) :448-454

[6] Hygiene hypothesis of asthma -: A murine asthma model with Mycoplasma pneumoniae infection [J].

Chu, HW ;

Honour, JM ;

Rawlinson, CA ;

Harbeck, RJ ;

Martin, RJ .

CHEST, 2003, 123 (03) :390S-390S

[7] Does early indoor microbial exposure reduce the risk of asthma? The Prevention and Incidence of Asthma and Mite Allergy birth cohort study [J].

Douwes, Jeroen ;

van Strien, Rob ;

Doekes, Gert ;

Smit, Jet ;

Kerkhof, Marian ;

Gerritsen, Jorrit ;

Postma, Dirkje ;

Travier, Noernie ;

Brunekreef, Bert .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2006, 117 (05) :1067-1073

[8] Toll-like receptor 2 as a major gene for asthma in children of European farmers [J].

Eder, W ;

Klimecki, W ;

Yu, LZ ;

von Mutius, E ;

Riedler, J ;

Braun-Fahrländer, C ;

Nowak, D ;

Martinez, FD .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2004, 113 (03) :482-488

[9] Prenatal farm exposure is related to the expression of receptors of the innate immunity and to atopic sensitization in school-age children [J].

Ege, MJ ;

Bieli, C ;

Frei, R ;

van Strien, RT ;

Riedler, J ;

Üblagger, E ;

Schram-Bijkerk, D ;

Brunekreef, B ;

van Hage, M ;

Scheynius, A ;

Pershagen, G ;

Benz, MR ;

Lauener, R ;

von Mutius, E ;

Braun-Fahrländer, C .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2006, 117 (04) :817-823

[10] HAY-FEVER, A POST INDUSTRIAL-REVOLUTION EPIDEMIC - A HISTORY OF ITS GROWTH DURING THE 19TH-CENTURY [J].

EMANUEL, MB .

CLINICAL ALLERGY, 1988, 18 (03) :295-304

← 1 2 3 4 →