Phenanthrenes from Juncus effusus with anxiolytic and sedative activities

被引：75

作者：

Wang, Yong-Gang ^{[1
]}

Wang, Yan-Long ^{[1
]}

Zhai, Hai-Feng ^{[2
]}

Liao, You-Jiao ^{[1
]}

Zhang, Bing ^{[1
]}

Huang, Jian-Mei ^{[1
]}

机构：

[1] Beijing Univ Chinese Med, Sch Chinese Mat Med, Beijing 100102, Peoples R China

[2] Peking Univ, Natl Inst Drug Dependence, Dept Neuropharmacol, Beijing 100191, Peoples R China

来源：

NATURAL PRODUCT RESEARCH | 2012年 / 26卷 / 13期

关键词：

Juncus effusus; dihydrophenanthrene; anxiolytic; sedative;

D O I：

10.1080/14786419.2011.561491

中图分类号：

O69 [应用化学];

学科分类号：

070301 [无机化学];

摘要：

Eight phenanthrenes, 7-carboxy-2-hydroxy-1-methyl-5-vinyl-phenanthrene (1); 2,7-dihydroxy-1-methyl-5-aldehyde-9,10-dihydrophenanthrene (2); dehydroeffusol (3); dehydrojuncusol (4); 7-carboxy-2-hydroxy-1-methyl-5-vinyl-9,10-dihydrophenanthrene (5); 8-carboxy-2-hydroxy-1-methyl-5-vinyl-9,10-dihydrophenanthrene (6); effusol (7) and juncusol (8), were isolated from the aerial part of Juncus effusus. Compounds 1 and 2 were identified as new constituents. Compounds 7 and 8 showed anxiolytic and sedative activities.

引用

页码：1234 / 1239

页数：6

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