Analgesic effect of intravenous pamidronate on chronic back pain due to osteoporotic vertebral fractures

被引：41

作者：

Gangji, V ^{[1
]}

Appelboom, T ^{[1
]}

机构：

[1] Free Univ Brussels, Hop Erasme, Dept Rheumatol, B-1070 Brussels, Belgium

来源：

CLINICAL RHEUMATOLOGY | 1999年 / 18卷 / 03期

关键词：

bisphosphonate; low back pain; osteoporosis;

D O I：

10.1007/s100670050099

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

Pamidronate, a bisphosphonate analogue has been evaluated in a retrospective study for its analgesic effect on chronic back pain due to vertebral fractures in 26 patients suffering from senile osteoporosis or glucocorticoid-induced osteoporosis. Sixty milligrams of pamidronate was administered intravenously every 3 months for one year. After three months of treatment, the pain score fell from 3.2 +/- 0.1 to 1.2 +/- 0.2 in both groups. In conclusion, intravenous pamidronate seems to be a valuable treatment for chronic back pain due to osteoporotic vertebral fractures.

引用

页码：266 / 267

页数：2

共 8 条

[1]

Intermittent etidronate therapy to prevent corticosteroid-induced osteoporosis [J].

Adachi, JD ;

Bensen, WG ;

Brown, J ;

Hanley, D ;

Hodsman, A ;

Josse, R ;

Kendler, DL ;

Lentle, B ;

Olszynski, W ;

SteMarie, LG ;

Tenenhouse, A ;

Chines, AA .

NEW ENGLAND JOURNAL OF MEDICINE, 1997, 337 (06) :382-387

[2]

GLOVER D, 1994, CANCER, V74, P2949, DOI 10.1002/1097-0142(19941201)74:11<2949::AID-CNCR2820741110>3.0.CO

[3]

2-Q

[4]

Efficacy of pamidronate in reducing skeletal complications in patients with breast cancer and lytic bone metastases [J].

Hortobagyi, GN ;

Theriault, RL ;

Porter, L ;

Blayney, D ;

Lipton, A ;

Sinoff, C ;

Wheeler, H ;

Simeone, JF ;

Seaman, J ;

Knight, RD ;

Heffernan, M ;

Reitsma, DJ .

NEW ENGLAND JOURNAL OF MEDICINE, 1996, 335 (24) :1785-1791

[5]

EFFECT OF ORAL ALENDRONATE ON BONE-MINERAL DENSITY AND THE INCIDENCE OF FRACTURES IN POSTMENOPAUSAL OSTEOPOROSIS [J].

LIBERMAN, UA ;

WEISS, SR ;

BROLL, J ;

MINNE, HW ;

QUAN, H ;

BELL, NH ;

RODRIGUEZPORTALES, J ;

DOWNS, RW ;

DEQUEKER, J ;

FAVUS, M ;

SEEMAN, E ;

RECKER, RR ;

CAPIZZI, T ;

SANTORA, AC ;

LOMBARDI, A ;

SHAH, RV ;

HIRSCH, LJ ;

KARPF, DB .

NEW ENGLAND JOURNAL OF MEDICINE, 1995, 333 (22) :1437-1443

[6]

Quality of life as outcome in the treatment of osteoporosis: The development of a questionnaire for quality of life by the European foundation for osteoporosis [J].

Lips, P ;

Cooper, C ;

Agnusdei, D ;

Caulin, F ;

Egger, P ;

Johnell, O ;

Kanis, JA ;

Liberman, U ;

Minne, H ;

Reeve, J ;

Reginster, JY ;

deVernejoul, MC ;

Wiklund, I .

OSTEOPOROSIS INTERNATIONAL, 1997, 7 (01) :36-38

[7]

PECK WA, 1993, AM J MED, V94, P646

[8]

Risedronate in the treatment of Paget's disease of bone: An open label, multicenter study [J].

Siris, ES ;

Chines, AA ;

Altman, RD ;

Brown, JP ;

Johnston, CC ;

Lang, R ;

Mcclung, MR ;

Mallette, LE ;

Miller, PD ;

Ryan, WG ;

Singer, FR ;

Tucci, JR ;

Eusebio, RA ;

Bekker, PJ .

JOURNAL OF BONE AND MINERAL RESEARCH, 1998, 13 (06) :1032-1038

← 1 →