Histological evaluation of liver in two rheumatoid arthritis patients with chronic hepatitis B and C treated with TNF-alpha blockade: case reports

被引：29

作者：

Kaur, Primal P. ^{[1
]}

Chan, Virginia C. ^{[2
]}

Berney, Steven N. ^{[1
]}

机构：

[1] Temple Univ, Sch Med, Dept Med, Div Rheumatol, Philadelphia, PA 19140 USA

[2] Kaiser Permanente, Imperial Orchard Med Off, Downey, CA USA

来源：

CLINICAL RHEUMATOLOGY | 2008年 / 27卷 / 08期

关键词：

hepatitis B; hepatitis C; rheumatoid arthritis; TNF-alpha blockers;

D O I：

10.1007/s10067-008-0896-y

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

Tumor necrosis factor (TNF)-alpha antagonists successfully modulate the pathogenesis of rheumatoid arthritis (RA). However, little is known about the effect of TNF-alpha blockade on the histology of chronic viral hepatitis. We describe the cases of two patients with RA, one with concurrent chronic hepatitis B virus and the other with hepatitis C virus infection who, as part of their evaluation, underwent liver biopsies while undergoing treatment with a TNF-alpha antagonist.

引用

页码：1069 / 1071

页数：3

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