Comparative antibacterial activity of polymeric 3-alkylpyridinium salts isolated from the Mediterranean sponge Reniera sarai and their synthetic analogues

被引：28

作者：

Chelossi, Elisabetta

Mancini, Ines

Sepcic, Kristina

Turk, Tom

Faimali, Marco

机构：

[1] CNR, Sect Marine Technol, Inst Marine Sci, I-16149 Genoa, Italy

[2] Univ Trent, Dept Phys, Bioorgan Chem Lab, I-38050 Trento, Italy

[3] Univ Ljubljana, Biotechnol Fac, Dept Biol, Ljubljana 1000, Slovenia

来源：

BIOMOLECULAR ENGINEERING | 2006年 / 23卷 / 06期

关键词：

alkaloids; alkylpyridinium; antibacterial; marine bacteria; marine sponge; MIC; Reniera sarai;

D O I：

10.1016/j.bioeng.2006.09.005

中图分类号：

Q5 [生物化学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

Metabolites from marine sponges are considered a promising alternative to heavy metals in antifouling coatings. Water-soluble polymeric 3-alkylpyridinium salts and 14 related synthetic analogues showed considerable antibacterial activity against marine biofilm bacteria and may represent good candidates as natural biocides for marine technology applications. (c) 2006 Elsevier B.V. All rights reserved.

引用

页码：317 / 323

页数：7

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