Case report - Suppression of symptoms of alcohol dependence and craving using high-dose baclofen

被引：78

作者：

Bucknam, William

机构：

[1] Ann Arbor, MI 48105, No. 207

来源：

ALCOHOL AND ALCOHOLISM | 2007年 / 42卷 / 02期

关键词：

D O I：

10.1093/alcalc/agl091

中图分类号：

R194 [卫生标准、卫生检查、医药管理];

学科分类号：

摘要：

Aims: To further test whether the baclofen-induced suppression of motivation to consume alcohol in animals could be transposed to humans. Methods: A patient who had neither tolerated nor benefited from other alcohol treatment modalities was put on trial with baclofen on a dosage up to 140 mg/day. Results: The patient reported dramatic reduction in cravings for and preoccupation with alcohol. Conclusions: High-dose baclofen therapy was associated with complete and prolonged suppression of symptoms and consequences of alcohol-dependence.

引用

页码：158 / 160

页数：3

共 17 条

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