Synthesis and antibacterial property of zinc loaded hydroxyapatite nanorods

被引：59

作者：

Chen, Xi ^{[2
,3
]}

Tang, Qi-Li ^{[1
]}

Zhu, Ying-Jie ^{[1
]}

Zhu, Cai-Lian ^{[3
]}

Feng, Xi-Ping ^{[2
,3
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, Shanghai 200050, Peoples R China

[2] Shanghai Jiao Tong Univ, Sch Med, Shanghai Peoples Hosp 9, Dept Prevent & Pediat Dent, Shanghai 200011, Peoples R China

[3] Shanghai Ninth Peoples Hosp, Shanghai Key Lab Stomatol, Shanghai 200011, Peoples R China

来源：

MATERIALS LETTERS | 2012年 / 89卷

关键词：

Calcium phosphate; Hydroxyapatite; Zinc; Antibacterial; Nanocomposite; Biomaterials;

D O I：

10.1016/j.matlet.2012.08.115

中图分类号：

T [工业技术];

学科分类号：

120111 [工业工程];

摘要：

In this work, hydroxyapatite (HAP) nanorods and amorphous calcium phosphate (ACP) nanoparticles have been prepared using CaCl2 center dot 2H(2)O and Na2HPO4 center dot 12H(2)O in aqueous solution and they are used as the nanocarriers for zinc loading. The "extraction" method is adopted for zinc loading, which is conducted in ethanol, the poor solvent for zinc acetate. Zinc loaded HAP nanorods and ACP nanoparticles are investigated for oral antibacterial application. The zinc loaded hydroxyapatite (Zn/HAP) nanorods has a favorable Zn2+ ion release property. While for zinc loaded ACP (Zn/ACP) nanoparticles, the Zn2+ ions can hardly be released. Antibacterial experiments show that Zn/HAP nanorods has the best performance to inhibit oral cavity bacteria Aggregaribacter actinomycetemcomitans. Fusobacterium nucleatum and Streptococcus mutans. The present method provides a new perspective to the preparation of antibacterial nanomaterials for oral care application. (C) 2012 Elsevier B.V. All rights reserved.

引用

页码：233 / 235

页数：3

共 18 条

[1]

Electrocrystallization of nanocrystallite calcium phosphate coatings on titanium substrate at different current densities [J].