Triterpenes, a sterol and a monocyclic alcohol from Momordica charantia

被引：44

作者：

Begum, S ^{[1
]}

Ahmed, M ^{[1
]}

Siddiqui, BS ^{[1
]}

Khan, A ^{[1
]}

Saify, ZS ^{[1
]}

Arif, M ^{[1
]}

机构：

[1] UNIV KARACHI,DEPT PHARMACEUT CHEM,KARACHI 75270,PAKISTAN

来源：

PHYTOCHEMISTRY | 1997年 / 44卷 / 07期

关键词：

Momordica charantia; Cucurbitaceae; pentacyclic triterpenes; sterol; monocyclic alcohol;

D O I：

10.1016/S0031-9422(96)00615-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Five new compounds have been isolated from the fresh fruits of Momordica charantia and their structures elucidated through spectroscopic studies. These include three pentacyclic triterpenes 13-hydroxy-28-methoxy-urs-11-en-3-one (momordicin), 13 beta,28-epoxy-urs-11-en-3-one (momordicinin), 24-[1'-hydroxy,1'-methyl-2'-pentenyloxyl]-ursan-3-one (momordicilin), a sterol 3 beta-hydroxy-stigmasta-5,14-dien-16-one (momordenol) and a monocyclic alcohol 1-hydroxy-1,2-dimethyl-2-[8',10'-dihydroxy-4',7'-dimethyl-11'-hydroxy methyl-trideca]-3-ethyl-cyclohex-5-en-4-one (momordol). Copyright (C) 1997 Elsevier Science Ltd.

引用

页码：1313 / 1320

页数：8

共 17 条

[1]

ALAM MS, 1994, PHYTOCHEMISTRY, V37, P521, DOI 10.1016/0031-9422(94)85091-7

[2] CLINICAL-TRIAL IN PATIENTS WITH DIABETES-MELLITUS OF AN INSULIN-LIKE COMPOUND OBTAINED FROM PLANT SOURCE [J].

BALDWA, VS ;

BHANDARI, CM ;

PANGARIA, A ;

GOYAL, RK .

UPSALA JOURNAL OF MEDICAL SCIENCES, 1977, 82 (01) :39-41

[3] CYTOTOXIC SAPONINS FROM NEW-ZEALAND MYRSINE SPECIES [J].

BLOOR, SJ ;

QI, L .

JOURNAL OF NATURAL PRODUCTS, 1994, 57 (10) :1354-1360

[4]

Breitmaier E, 1979, ATLAS CARBON 13 NMR, V1

[5]

Chopra R.N., 1958, Indigenous Drugs of India, V2nd

[6]

Fiaud J. C., 1977, STEREOCHEMISTRY FUND, V3

[7] COMPLETE H-1 AND C-13 RESONANCE ASSIGNMENT OF 27-NORURS-13-EN-3-BETA-ACETYLOXY-28-OIC ACID BY NMR-SPECTROSCOPY [J].

JIMENO, ML ;

RUMBERO, A ;

VAZQUEZ, P .

MAGNETIC RESONANCE IN CHEMISTRY, 1995, 33 (05) :408-411

[8]

JOHNSON LF, 1978, CARBON 13 NMR SPECTR

[9] CONSTITUENTS OF THE LABIATAE PLANTS .4. CONFIGURATIONAL STUDIES ON HYDROXY-GROUPS AT C-2 C-3 AND C-23 OR C-24 OF OLEANENE AND URSENE-TYPE TRITERPENES BY NMR-SPECTROSCOPY [J].

KOJIMA, H ;

OGURA, H .

PHYTOCHEMISTRY, 1989, 28 (06) :1703-1710

[10]

KRITIKAR KR, 1918, INDIAN MED PLANTS, P590

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