Positron emission tomography in juvenile Alexander disease

被引：10

作者：

Sawaishi, Y

Hatazawa, J

Ochi, N

Hirono, H

Yano, T

Watanabe, Y

Okudera, T

Takada, G

机构：

[1] Akita Univ, Sch Med, Dept Pediat, Akita 0108543, Japan

[2] Res Inst Brain & Blood Vessels, Dept Radiol & Nucl Med, Akita 0100874, Japan

[3] Second Aoitori Gakuen, Okazaki, Aichi 4443505, Japan

来源：

JOURNAL OF THE NEUROLOGICAL SCIENCES | 1999年 / 165卷 / 02期

关键词：

Alexander disease; leukodystrophy; MRI; FDG; PET; vertebra; alpha B-crystallin; heat shock protein 27;

D O I：

10.1016/S0022-510X(99)00090-8

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A 13-year-old boy with cervical kyphosis was diagnosed as having juvenile Alexander disease because of the typical MRI findings, abnormally elevated alpha B-crystallin and heat shock protein 27 in the cerebrospinal fluid. Positron emission tomography with F-18-fluoro-deoxyglucose demonstrated hypometabolism in the frontal white matter corresponding to the areas with leukodystrophy. However, the overlying gray matter preserved normal glucose metabolism. (C) 1999 Elsevier Science B.V. All rights reserved.

引用

收藏

页码：116 / 120

页数：5

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