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Cancer immunotherapy: synthetic and natural peptides in the balance

被引：27
作者：
Bellone, M
Iezzi, G
Imro, MA
Protti, MP
机构：
[1] Inst Sci H San Raffaele, Lab Tumor Immunol, I-20132 Milan, Italy
[2] Inst Sci H San Raffaele, Canc Immunotherapy & Gene Therapy Program, I-20132 Milan, Italy
来源：
IMMUNOLOGY TODAY | 1999年 / 20卷 / 10期
关键词：
D O I：
10.1016/S0167-5699(99)01503-0
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The identification of human tumor-associated antigens has opened new avenues for immune intervention in cancer. Clinical trials using synthetic peptides that match segments of known tumor-associated proteins are ongoing. Alternatively, naturally processed peptides, obtained by acid treatment of tumor cells can be used. Here, Matteo Bellone and colleagues discuss the advantages and disadvantages of synthetic versus natural tumor peptides in cancer immunotherapy.
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页码：457 / 462
页数：6
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