A tense time for the nuclear envelope

被引:11
作者
Aitchison, JD
Rout, MP
机构
[1] Rockefeller Univ, New York, NY 10021 USA
[2] Inst Syst Biol, Seattle, WA USA
关键词
D O I
10.1016/S0092-8674(02)00638-4
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
When many cells divide, the nuclear envelope poses a problem: the spindle microtubules can't access the chromosomes. Two recent papers in Cell describe how the spindle solves this problem by literally pulling open the nucleus at the beginning of mitosis.
引用
收藏
页码:301 / 304
页数:4
相关论文
共 20 条
[1]   Nuclear envelope breakdown proceeds by microtubule-induced tearing of the lamina [J].
Beaudouin, J ;
Gerlich, D ;
Daigle, N ;
Eils, R ;
Ellenberg, J .
CELL, 2002, 108 (01) :83-96
[2]  
BUSSON S, 1997, CELL STRUCT FUNCT, V22, P621
[3]   Sorting nuclear membrane proteins at mitosis [J].
Collas, P ;
Courvalin, JC .
TRENDS IN CELL BIOLOGY, 2000, 10 (01) :5-8
[4]   Nuclear pore complexes form immobile networks and have a very low turnover in live mammalian cells [J].
Daigle, N ;
Beaudouin, J ;
Hartnell, L ;
Imreh, G ;
Hallberg, E ;
Lippincott-Schwartz, J ;
Ellenberg, J .
JOURNAL OF CELL BIOLOGY, 2001, 154 (01) :71-84
[5]   Nup2p dynamically associates with the distal regions of the yeast nuclear pore complex [J].
Dilworth, DJ ;
Suprapto, A ;
Padovan, JC ;
Chait, BT ;
Wozniak, RW ;
Rout, MP ;
Aitchison, JD .
JOURNAL OF CELL BIOLOGY, 2001, 153 (07) :1465-1478
[6]  
ELLENBERG J, 1997, BIOCHEM BIOPH RES CO, V238, P240
[7]  
GANT TM, 1997, ANNU REV GENET, V31, P277
[8]  
Georgatos SD, 1997, J CELL SCI, V110, P2129
[9]   The inner nuclear membrane: simple, or very complex? [J].
Georgatos, SD .
EMBO JOURNAL, 2001, 20 (12) :2989-2994
[10]   Cytoplasmic dynein is required for distinct aspects of MTOC positioning, including centrosome separation, in the one cell stage Caenorhabditis elegans embryo [J].
Gönczy, P ;
Pichler, S ;
Kirkham, M ;
Hyman, AA .
JOURNAL OF CELL BIOLOGY, 1999, 147 (01) :135-150