Influence of surgical strategies on outcome after the Norwood procedure

被引:39
作者
Griselli, M
McGuirk, SP
Stümper, O
Clarke, AJB
Miller, P
Dhillon, R
Wright, JGC
de Giovanni, JV
Barron, DJ
Brawn, WJ
机构
[1] Diana Princess Wales Childrens Hosp, Dept Pediat Cardiac Surg, Birmingham B4 6NH, W Midlands, England
[2] Diana Princess Wales Childrens Hosp, Dept Pediat Cardiol, Birmingham B4 6NH, W Midlands, England
关键词
D O I
10.1016/j.jtcvs.2005.08.066
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective: The study objective was to identify how the evolution of surgical strategies influenced the outcome after the Norwood procedure. Methods: From 1992 to 2004, 367 patients underwent the Norwood procedure (median age, 4 days). Three surgical strategies were identified on the basis of arch reconstruction and source of pulmonary blood flow. The arch was refashioned without extra material in group A (n = 148). The arch was reconstructed with a pulmonary artery homograft patch in groups B (n = 145) and C (n = 74). Pulmonary blood flow was supplied by a modified Blalock-Taussig shunt in groups A and B. Pulmonary blood flow was supplied by a right ventricle to pulmonary artery conduit in group C. Early mortality, actuarial survival, and freedom from arch reintervention or pulmonary artery patch augmentation were analyzed. Results: Early mortality was 28% (n = 102). Actuarial survival was 62% +/- 3% at 6 months. Early mortality was lower in group C (15%) than group A (31%) or group B (31%; P < .05). Actuarial survival at 6 months was better in group C (78% +/- 5%) than group A (59% +/- 5%) or group B (58% +/- 4%; P < .05). Fifty-three patients (14%) had arch reintervention. Freedom from arch reintervention was 76% +/- 3% at 1 year, with univariable analysis showing no difference among groups A, B, and C (P = .71). One hundred patients (27%) required subsequent pulmonary artery patch augmentation. Freedom from patch augmentation was 61% +/- 3% at I year, and was lower in group C (3% +/- 3%) than group A (80% +/- 4%) or group B (72% +/- 5%; P < .05). Conclusions: Survival after the Norwood procedure improved after the introduction of a right ventricle to pulmonary artery conduit, but a greater proportion of patients required subsequent pulmonary artery patch augmentation. The type of arch reconstruction did not affect the incidence of arch reintervention.
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页码:418 / 426
页数:9
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