Anti-pathogenic Potential of Coral Associated Bacteria Isolated from Gulf of Mannar Against Pseudomonas aeruginosa

被引：21

作者：

Bakkiyaraj, Dhamodharan ^{[1
]}

Sivasankar, Chandran ^{[1
]}

Pandian, Shunmugiah Karutha ^{[1
]}

机构：

[1] Alagappa Univ, Dept Biotechnol, Karaikkudi 630003, Tamil Nadu, India

来源：

INDIAN JOURNAL OF MICROBIOLOGY | 2013年 / 53卷 / 01期

关键词：

Quorum sensing; Pseudomonas aeruginosa; Coral associated bacteria; Biofilm; Anti-QS; Quorum sensing inhibitor; QUORUM; INHIBITION; ANTAGONISTS;

D O I：

10.1007/s12088-012-0342-3

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 [微生物学]; 090105 [作物生产系统与生态工程];

摘要：

Infections of Pseudomonas aeruginosa are of great concern because of its increasing resistance towards conventional antibiotics. Quorum sensing system of P. aeruginosa acts as a global regulator of almost all the virulence factors and majorly its biofilm formation. In the present study, quenching of QS system of P. aeruginosa has been explained with bioactives from bacteria associated with the coral Acropora digitifera. Isolated bioactives inhibited the expression of various virulence traits of P. aeruginosa like biofilm formation, and the production of extracellular enzymes like protease and elastase. This study also emphasises the potential of coral associated bacteria in producing bioactive agents with anti-pathogenic properties.

引用

页码：111 / 113

页数：3

共 12 条

[1]

Inhibition of quorum sensing-controlled virulence factor production in Pseudomonas aeruginosa by south Florida plant extracts [J].