The synthesis of alkyl carbamates from primary aliphatic amines and dialkyl carbonates in supercritical carbon dioxide

被引：70

作者：

Selva, M ^{[1
]}

Tundo, P ^{[1
]}

Perosa, A ^{[1
]}

机构：

[1] Univ Ca Foscari, Dipartimento Sci Ambientali, I-30123 Venice, Italy

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 07期

关键词：

D O I：

10.1016/S0040-4039(01)02390-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

At 130degreesC and in the presence of compressed CO2, primary aliphatic amines [RNH2, R=C10H21, C8H17, cHex. 1-(C10H7)CH2] react with organic carbonates (R'OCO2R': R' = Me, Et) to give alkyl carbamates (RNHCO2R', 1). Although CO2 promotes the reaction also at a low pressure, good yields (similar to80%) of 1 are achievable only with supercritical carbon dioxide (scCO(2)) at 90 bar, which inhibits the forniation of N-methylated by-products. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：1217 / 1219

页数：3

共 27 条

[1] The kinetics and mechanism of the reaction between carbon dioxide and a series of amines - Observation and interpretation of an isokinetic effect [J].