Recommendations of the National Heart, Lung, and Blood Institute working group on cerebrovascular biology and disease

被引:29
作者
Iadecola, Costantino
Goldman, Stephen S.
Harder, David R.
Heistad, Donald D.
Katusic, Zvonimir S.
Moskowitz, Michael A.
Simard, J. Marc
Sloan, Michael A.
Traystman, Richard J.
Velletri, Paul A.
机构
[1] NHLBI, Bethesda, MD 20892 USA
[2] Weill Cornell Med Coll, New York, NY USA
[3] Med Coll Wisconsin, Milwaukee, WI USA
[4] Univ Iowa, Iowa City, IA USA
[5] Mayo Clin Coll Med, Rochester, MN USA
[6] Massachusetts Gen Hosp, Charlestown, MA USA
[7] Univ Maryland, Sch Med, Baltimore, MD 21201 USA
[8] Carolinas Med Ctr, Charlotte, NC 28203 USA
[9] Oregon Hlth Sci Univ, Sch Med, Portland, OR 97201 USA
关键词
cerebrovascular disease; microcirculation;
D O I
10.1161/01.STR.0000221297.57305.8a
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The National Heart, Lung, and Blood Institute (NHLBI) convened a conference call working group, consisting of experts in stroke and cerebrovascular biology on January 28, 2005. The purpose of this working group was to develop a prioritized set of recommendations for NHLBI to establish a focused and comprehensive set of research activities in cerebrovascular biology and disease. Three thematic areas of research emerged: (1) molecular and cellular neurobiology of cerebral blood vessels, focusing on genomics and proteomics, neurovascular signaling and cerebrovascular embryogenesis, development and plasticity; (2) resource development, involving the development of new methodological approaches for normal and altered function of the neurovascular unit, collaborative research, and training in cerebrovascular pathobiology; and (3) cerebrovascular diseases and translational approaches, addressing vascular mechanisms of disease, the role of risk factors, importance of biomarkers with the ultimate goal of developing new treatments.
引用
收藏
页码:1578 / 1581
页数:4
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