Diffuse axonal injuries: pathophysiology and imaging

被引:75
作者
Hammoud, DA [1 ]
Wassennan, BA [1 ]
机构
[1] Johns Hopkins Univ, Div Neuroradiol, Sch Med, Baltimore, MD 21287 USA
关键词
D O I
10.1016/S1052-5149(02)00011-4
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Diffuse axonal injury (DAI) is the sequela of shear-strain injury to the brain, and occurs in almost half of serious traumatic brain injuries, both in adults and children. This article discusses the mechanism and pathophysiology of axonal shear injury as well as the clinical presentation and prognostic factors of DAI patients. The different imaging modalities are discussed, with emphasis on both classical and new modalities.
引用
收藏
页码:205 / +
页数:13
相关论文
共 42 条
[1]   Functional recovery after brain lesion - contralateral neuromodulation: an fMRI study [J].
Abo, M ;
Chen, ZG ;
Lai, LJ ;
Reese, T ;
Bjelke, B .
NEUROREPORT, 2001, 12 (07) :1543-1547
[2]   Detection of acute pathologic changes following experimental traumatic brain injury using diffusion-weighted magnetic resonance imaging [J].
Alsop, DC ;
Murai, H ;
Detre, JA ;
McIntosh, TK ;
Smith, DH .
JOURNAL OF NEUROTRAUMA, 1996, 13 (09) :515-521
[3]   MRI of head injury using FLAIR [J].
Ashikaga, R ;
Araki, Y ;
Ishida, O .
NEURORADIOLOGY, 1997, 39 (04) :239-242
[4]   Neuroimaging correlates of cognitive and functional outcome after traumatic brain injury [J].
Azouvi, P .
CURRENT OPINION IN NEUROLOGY, 2000, 13 (06) :665-669
[5]  
Bagley LJ, 2000, J MAGN RESON IMAGING, V11, P1, DOI 10.1002/(SICI)1522-2586(200001)11:1<1::AID-JMRI1>3.0.CO
[6]  
2-H
[7]   Contribution of vasogenic and cellular edema to traumatic brain swelling measured by diffusion-weighted imaging [J].
Barzo, P ;
Marmarou, A ;
Fatouros, P ;
Hayasaki, K ;
Corwin, F .
JOURNAL OF NEUROSURGERY, 1997, 87 (06) :900-907
[8]  
Bigler E D, 1999, Appl Neuropsychol, V6, P217, DOI 10.1207/s15324826an0604_4
[9]  
Bigler ED, 1997, AM J NEURORADIOL, V18, P11
[10]   Magnetic resonance spectroscopy in traumatic brain injury [J].
Brooks, WM ;
Friedman, SD ;
Gasparovic, C .
JOURNAL OF HEAD TRAUMA REHABILITATION, 2001, 16 (02) :149-164