Nonclonal Emergence of Colistin-Resistant Klebsiella pneumoniae Isolates from Blood Samples in South Korea

被引：60

作者：

Suh, Ji-Yoeun ^{[2
]}

Son, Jun Seong ^{[3
]}

Chung, Doo Ryeon ^{[4
]}

Peck, Kyong Ran ^{[4
]}

Ko, Kwan Soo ^{[1
,2
]}

Song, Jae-Hoon ^{[2
,4
]}

机构：

[1] Sungkyunkwan Univ, Dept Mol Cell Biol, Sch Med, Suwon 440746, South Korea

[2] Asian Pacific Res Fdn Infect Dis, Seoul, South Korea

[3] Kyunghee Univ Hosp, Seoul, South Korea

[4] Sungkyunkwan Univ, Div Infect Dis, Samsung Med Ctr, Sch Med, Seoul, South Korea

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2010年 / 54卷 / 01期

关键词：

IN-VITRO ACTIVITY; POLYMYXIN-B; ACINETOBACTER-BAUMANNII; SUSCEPTIBILITY; EPIDEMIOLOGY; INFECTION; BROOKLYN;

D O I：

10.1128/AAC.00762-09

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

In vitro activities of colistin and other drugs were tested against 221 Klebsiella pneumoniae isolates that were collected between 2006 and 2007 in nine tertiary care South Korean hospitals from patients with bacteremia. The clonality of colistin-resistant K. pneumoniae (CRKP) isolates was assessed by multilocus sequence typing (MLST). We found that 15 isolates (6.8%) were resistant to colistin. MLST showed that CRKP isolates were nonclonal, with colistin resistance in K. pneumoniae occurring independently and not by clonal spreading.

引用

页码：560 / 562

页数：3

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