Medial prefrontal cell activity signaling prediction errors of action values

被引:324
作者
Matsumoto, Madoka
Matsumoto, Kenji
Abe, Hiroshi
Tanaka, Keiji
机构
[1] RIKEN, Brain Sci Inst, Cognit Brain Mapping Lab, Wako, Saitama 3510198, Japan
[2] Kyoto Univ, Inst Primate Res, Dept Behav & Brain Sci, Inuyama, Aichi 4848506, Japan
[3] Tokyo Inst Technol, Grad Sch Decis Sci & Technol, Meguro Ku, Tokyo 1528552, Japan
[4] Saitama Univ, Grad Sch Sci & Engn, Sakura Ku, Saitama 3388570, Japan
关键词
D O I
10.1038/nn1890
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
To adapt behavior to a changing environment, one must monitor outcomes of executed actions and adjust subsequent actions accordingly. Involvement of the medial frontal cortex in performance monitoring has been suggested, but little is known about neural processes that link performance monitoring to performance adjustment. Here, we recorded from neurons in the medial prefrontal cortex of monkeys learning arbitrary action- outcome contingencies. Some cells preferentially responded to positive visual feedback stimuli and others to negative feedback stimuli. The magnitude of responses to positive feedback stimuli decreased over the course of behavioral adaptation, in correlation with decreases in the amount of prediction error of action values. Therefore, these responses in medial prefrontal cells may signal the direction and amount of error in prediction of values of executed actions to specify the adjustment in subsequent action selections.
引用
收藏
页码:647 / 656
页数:10
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