RamB, the transcriptional regulator of acetate metabolism in Corynebacterium glutamicum, is subject to regulation by RamA and RamBv

被引:34
作者
Cramer, Annette
Auchter, Marc
Frunzke, Julia
Bott, Michael
Eikmanns, Bernhard J. [1 ]
机构
[1] Univ Ulm, Dept Microbiol & Biotechnol, D-89069 Ulm, Germany
[2] Res Ctr Julich, Inst Biotechnol 1, D-52425 Julich, Germany
关键词
D O I
10.1128/JB.01061-06
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
In Corynebacterium glutamicum, the transcriptional regulator RamB negatively controls the expression of genes involved in acetate metabolism. Here we show that RamB represses its own expression by direct interaction with a 13-bp motif in the ramB promoter region. Additionally, ramB expression is subject to carbon source-dependent positive control by RamA.
引用
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页码:1145 / 1149
页数:5
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