Desmosdumotin C, a novel cytotoxic principle from Desmos dumosus

被引：25

作者：

Wu, JH ^{[1
]}

McPhail, AT

Bastow, KF

Shiraki, H

Ito, J

Lee, KH

机构：

[1] Univ N Carolina, Sch Pharm, Nat Prod Lab, Chapel Hill, NC 27599 USA

[2] Duke Univ, Dept Chem, Paul M Gross Chem Lab, Durham, NC 27708 USA

[3] Hosp PLA 306, Dept Pharm, Beijing 100101, Peoples R China

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 08期

关键词：

desmosdumotin C; Desmos dumosus; cytotoxicity; antitumor;

D O I：

10.1016/S0040-4039(02)00026-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The structure of desmosdumotin C (1), a novel compared isolated from the roots of Desmos dumosus has been established from spectral data and X-ray crystallographic analysis. Significant and selective in vitro cytotoxicity of 1 was found against bone (HOS). breast (MCF), and ovarian (IA9) cancer cell lines. (C) 2002 Published by Elsevier Science Ltd.

引用

页码：1391 / 1393

页数：3