CAPILLARY ELECTROPHORESIS COUPLED TO MASS SPECTROMETRY (CE-MS): TWENTY YEARS OF DEVELOPMENT

被引：12

作者：

Assuncao, Nilson Antonio ^{[1
]}

Henriques Bechara, Etelvino Jose ^{[1
]}

Colnaghi Simionato, Ana Valeria ^{[2
]}

Maggi Tavares, Marina Franco ^{[2
]}

Carrilho, Emanuel

机构：

[1] Univ Sao Paulo, Inst Quim, Dept Bioquim, BR-05513970 Sao Paulo, Brazil

[2] Univ Sao Paulo, Inst Quim, Dept Quim Fundamental, BR-05513970 Sao Paulo, Brazil

来源：

QUIMICA NOVA | 2008年 / 31卷 / 08期

关键词：

capillary electrophoresis; electrospray ionization; mass spectrometry;

D O I：

10.1590/S0100-40422008000800037

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

CE-MS has been increasingly used for analysis of a vast array of compounds. This article reviews the different electrophoretic modes, interfaces and mass analyzers that are commonly used in the CE-MS coupling, as well as the technique advantages and performance characteristics. A large compilation of CE-MS applications is also presented. Therefore, this review is both a guide for beginners and a collection of key references for people who are familiar to the technique. Furthermore, this is the first CE-MS review published in a Brazilian journal and marks the installation of the first two commercial CE-MS units in Sao Paulo State.

引用

页码：2124 / 2133

页数：10

共 163 条

[71]

MISCHAK H, 2004, CLIN SCI, V7, P85

[72] On-line capillary electrophoresis-mass spectrometry using dopant-assisted atmospheric pressure photoionization: Setup and system performance [J].

Mol, R ;

de Jong, GJ ;

Somsen, GW .

ELECTROPHORESIS, 2005, 26 (01) :146-154

[73] OPTIMIZATION OF A COAXIAL CONTINUOUS-FLOW FAST ATOM BOMBARDMENT INTERFACE BETWEEN CAPILLARY LIQUID-CHROMATOGRAPHY AND MAGNETIC-SECTOR MASS-SPECTROMETRY FOR THE ANALYSIS OF BIOMOLECULES [J].

MOSELEY, MA ;

DETERDING, LJ ;

DEWIT, JSM ;

TOMER, KB ;

KENNEDY, RT ;

BRAGG, N ;

JORGENSON, JW .

ANALYTICAL CHEMISTRY, 1989, 61 (14) :1577-1584

[74] COUPLING OF CAPILLARY ZONE ELECTROPHORESIS AND CAPILLARY LIQUID-CHROMATOGRAPHY WITH COAXIAL CONTINUOUS-FLOW FAST ATOM BOMBARDMENT TANDEM SECTOR MASS-SPECTROMETRY [J].

MOSELEY, MA ;

DETERDING, LJ ;

TOMER, KB ;

JORGENSON, JW .

JOURNAL OF CHROMATOGRAPHY, 1989, 480 :197-209

[75] CAPILLARY ZONE ELECTROPHORESIS MASS-SPECTROMETRY USING A COAXIAL CONTINUOUS-FLOW FAST-ATOM-BOMBARDMENT INTERFACE [J].

MOSELEY, MA ;

DETERDING, LJ ;

TOMER, KB ;

JORGENSON, JW .

JOURNAL OF CHROMATOGRAPHY, 1990, 516 (01) :167-173

[76] Direct coupling of polymer-based microchip electrophoresis to online MALDI-MS using a rotating ball inlet [J].

Musyimi, HK ;

Guy, J ;

Narcisse, DA ;

Soper, SA ;

Murray, KK .

ELECTROPHORESIS, 2005, 26 (24) :4703-4710

[77] Mechanistic studies of partial-filling micellar electrokinetic chromatography [J].

Nelson, WM ;

Lee, CS .

ANALYTICAL CHEMISTRY, 1996, 68 (18) :3265-3269

[78]

NILSSON S, 2004, THESIS U UPPSALA SUE

[79] ONLINE MASS-SPECTROMETRIC DETECTION FOR CAPILLARY ZONE ELECTROPHORESIS [J].

OLIVARES, JA ;

NGUYEN, NT ;

YONKER, CR ;

SMITH, RD .

ANALYTICAL CHEMISTRY, 1987, 59 (08) :1230-1232

[80] Stereoselective separation and detection of phenoxy acid herbicide enantiomers by cyclodextrin-modified capillary zone electrophoresis electrospray ionization mass spectrometry [J].

Otsuka, K ;

Smith, CJ ;

Grainger, J ;

Barr, JR ;

Patterson, DG ;

Tanaka, N ;

Terabe, S .

JOURNAL OF CHROMATOGRAPHY A, 1998, 817 (1-2) :75-81

← 3 4 5 6 7 8 9 10 11 12 →