Mechanisms of disease - Bone quality - The material and structural basis of bone strength and fragility

被引：1415

作者：

Seeman, Ego ^{[1
]}

Delmas, Pierre D.

机构：

[1] Univ Melbourne, Austin Hlth, Dept Endocrinol, Melbourne, Vic 3084, Australia

[2] Univ Lyon 1, Dept Rheumatol, F-69365 Lyon, France

[3] INSERM, Res Unit 403, F-69008 Lyon, France

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2006年 / 354卷 / 21期

关键词：

D O I：

10.1056/NEJMra053077

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This review discusses advances in knowledge regarding the composition and structure of bone, the modeling and remodeling of bone, the formation of bone during growth and its reconstruction in adults, and how age-related abnormalities in these processes compromise the composition and structure of bone. Copyright © 2006 Massachusetts Medical Society.

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收藏

页码：2250 / 2261

页数：12

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