Life Years Lost Associated with Obesity-Related Diseases for US Non-Smoking Adults

被引:34
作者
Chang, Su-Hsin [1 ]
Pollack, Lisa M. [2 ]
Colditz, Graham A. [1 ]
机构
[1] Washington Univ, Sch Med, Dept Surg, Div Publ Hlth Sci, St Louis, MO 63110 USA
[2] Washington Univ, George Warren Brown Sch Social Work, St Louis, MO 63130 USA
关键词
BODY-MASS INDEX; WAIST-HIP RATIO; PROSPECTIVE COHORT; MORTALITY; OVERWEIGHT; WEIGHT; UNDERWEIGHT; HETEROGENEITY; CONSEQUENCES; EXPECTANCY;
D O I
10.1371/journal.pone.0066550
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
070301 [无机化学]; 070403 [天体物理学]; 070507 [自然资源与国土空间规划学]; 090105 [作物生产系统与生态工程];
摘要
The objectives of this paper are to predict life years lost associated with obesity-related diseases (ORDs) for U.S. non-smoking adults, and to examine the relationship between those ORDs and mortality. Data from the National Health Interview Survey, 1997-2000, were used. We employed mixed proportional hazard models to estimate the association between those ORDs and mortality and used simulations to project life years lost associated with the ORDs. We found that obesity-attributable comorbidities are associated with large decreases in life years and increases in mortality rates. The life years lost associated with ORDs is more marked for younger adults than older adults, for blacks than whites, for males than females, and for the more obese than the less obese. Using U. S. non-smoking adults aged 40 to 49 years as an example to illustrate percentage of the life years lost associated with ORDs, we found that the mean life years lost associated with ORDs for U. S. non-smoking black males aged 40 to 49 years with a body mass index above 40 kg/m(2) was 5.43 years, which translates to a 7.5% reduction in total life years. White males of the same age range and same degree of obesity lost 5.23 life years on average - a 6.8% reduction in total life years, followed by black females (5.04 years, a 6.5% reduction in life years), and white females (4.7 years, a 5.8% reduction in life years). Overall, ORDs increased chances of dying and lessened life years by 0.2 to 11.7 years depending on gender, race, BMI classification, and age.
引用
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页数:7
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