A case of pulmonary toxicity associated with G-CSF and doxorubicin administration

被引：15

作者：

Eisenbeis, CF

Winn, D

Poelman, S

Polsky, CV

Rubenstein, JH

Olopade, OI

机构：

[1] Univ Chicago, Med Ctr, Hematol Oncol Sect, Chicago, IL 60637 USA

[2] Univ Chicago, Med Ctr, Dept Med, Chicago, IL 60637 USA

来源：

ANNALS OF HEMATOLOGY | 2001年 / 80卷 / 02期

关键词：

G-CSF; doxorubicin; toxicity; pneumonitis;

D O I：

10.1007/s002770000232

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The cytokine growth factor, G-CSF (granulocyte colony-stimulating factor), is commonly used in oncologic practice and is generally believed to be a safe agent to administer. We describe here a case of pulmonary toxicity associated with the concurrent administration of G-CSF and doxorubicin. We contend that G-CSF contributed to the life-threatening lung injury in our patient, and discuss additional reports in the literature of pulmonary toxicity associated with the use of this agent.

引用

页码：121 / 123

页数：3

共 22 条

[1] Anaphylactoid reaction in a normal donor given granulocyte colony-stimulating factor [J].