Stereotactic Body Radiation Therapy for Stage I Non-Small Cell Lung Cancer

被引:11
作者
Aridgides, Paul [1 ]
Bogart, Jeffrey [1 ]
机构
[1] SUNY Upstate Med Univ, Dept Radiat Oncol, 750 E Adams St, Syracuse, NY 13210 USA
关键词
Stereotactic body radiation therapy; SBRT; Stage I non-small cell lung cancer; NSCLC; Medically inoperable; Medically operable; ABLATIVE RADIOTHERAPY; PHASE-II; PULMONARY-FUNCTION; CENTRAL TUMORS; TRIAL; SCHEDULES; OUTCOMES; SBRT; LOBECTOMY; CARCINOMA;
D O I
10.1016/j.thorsurg.2016.04.008
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
100201 [内科学];
摘要
Stereotactic body radiation therapy (SBRT) has had a profound impact on the treatment paradigm for medically inoperable patients with stage I non small cell lung cancer. Local control and survival outcomes from prospective collaborative trials using SBRT have been highly favorable in this challenging patient population. Further study in medically operable patients is ongoing; however, randomized trials to help answer this question have terminated early because of poor accrual. Available prospective and retrospective data are discussed for the use of SBRT with regard to the medically inoperable and operable patient populations, as well as considerations for fractionation, dose, and toxicity.
引用
收藏
页码:261 / +
页数:10
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