American Geriatrics Society Updated Beers Criteria for Potentially Inappropriate Medication Use in Older Adults

被引:1553
作者
Fick, Donna [2 ,3 ]
Semla, Todd [4 ,5 ]
Beizer, Judith [6 ]
Dombrowski, Robert [8 ]
Brandt, Nicole [7 ]
DuBeau, Catherine E. [9 ]
Flanagan, Nina [10 ]
Hanlon, Joseph [11 ,12 ]
Hollmann, Peter [13 ]
Linnebur, Sunny [14 ]
Nau, David [15 ]
Rehm, Bob [16 ]
Sandhu, Satinderpal [17 ,18 ]
Steinman, Michael [19 ,20 ]
机构
[1] Amer Geriatr Soc, New York, NY USA
[2] Penn State Univ, Sch Nursing, University Pk, PA 16802 USA
[3] Penn State Univ, Coll Med, Dept Psychiat, University Pk, PA 16802 USA
[4] Natl Pharm Benefits Management Serv, US Dept Vet Affairs, Chicago, IL USA
[5] Northwestern Univ, Chicago, IL 60611 USA
[6] St Johns Univ, New York, NY USA
[7] Univ Maryland, Baltimore, MD 21201 USA
[8] Ctr Medicare & Medicaid Serv, Baltimore, MD USA
[9] Univ Massachusetts, Sch Med, Worcester, MA USA
[10] Binghamton Univ, Dunmore, PA USA
[11] Univ Pittsburgh, Sch Med, Dept Med Geriatr Med, Pittsburgh, PA USA
[12] Vet Adm Hlth Syst, Geriatr Educ & Res & Clin Ctr, Pittsburgh, PA USA
[13] Blue Cross Blue Shield Rhode Isl, Cranston, RI USA
[14] Univ Colorado, Sch Pharm & Pharmaceut Sci, Aurora, CO USA
[15] Pharm Qual Alliance Inc, Baltimore, MD USA
[16] Natl Comm Qual Assurance, Washington, DC USA
[17] MetroHlth Med Ctr, Cleveland, OH USA
[18] Case Western Reserve Univ, Sch Med, Cleveland, OH USA
[19] Univ Calif San Francisco, San Francisco, CA 94143 USA
[20] San Francisco VA Med Ctr, San Francisco, CA USA
基金
美国医疗保健研究与质量局;
关键词
Beers list; medications; Beers Criteria; drugs; older adults; ADVERSE DRUG-REACTIONS; EXPLICIT CRITERIA; EVENTS; SCALE; AGE;
D O I
10.1111/j.1532-5415.2012.03923.x
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Potentially inappropriate medications (PIMs) continue to be prescribed and used as first-line treatment for the most vulnerable of older adults, despite evidence of poor outcomes from the use of PIMs in older adults. PIMs now form an integral part of policy and practice and are incorporated into several quality measures. The specific aim of this project was to update the previous Beers Criteria using a comprehensive, systematic review and grading of the evidence on drug-related problems and adverse drug events (ADEs) in older adults. This was accomplished through the support of The American Geriatrics Society (AGS) and the work of an interdisciplinary panel of 11 experts in geriatric care and pharmacotherapy who applied a modified Delphi method to the systematic review and grading to reach consensus on the updated 2012 AGS Beers Criteria. Fifty-three medications or medication classes encompass the final updated Criteria, which are divided into three categories: potentially inappropriate medications and classes to avoid in older adults, potentially inappropriate medications and classes to avoid in older adults with certain diseases and syndromes that the drugs listed can exacerbate, and finally medications to be used with caution in older adults. This update has much strength, including the use of an evidence-based approach using the Institute of Medicine standards and the development of a partnership to regularly update the Criteria. Thoughtful application of the Criteria will allow for (a) closer monitoring of drug use, (b) application of real-time e-prescribing and interventions to decrease ADEs in older adults, and (c) better patient outcomes. © 2012, Copyright the Authors Journal compilation © 2012, The American Geriatrics Society.
引用
收藏
页码:616 / 631
页数:16
相关论文
共 35 条
[1]   Use of a computer-based reminder to improve sedative-hypnotic prescribing in older hospitalized patients [J].
Agostini, Joseph V. ;
Zhang, Ying ;
Inouye, Sharon K. .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2007, 55 (01) :43-48
[2]   DESIGNING AND EXECUTING RANDOMIZED CLINICAL-TRIALS INVOLVING ELDERLY PERSONS [J].
APPLEGATE, WB ;
CURB, JD .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 1990, 38 (08) :943-950
[3]  
BEERS MH, 1991, ARCH INTERN MED, V151, P1825
[4]   Explicit criteria for determining potentially inappropriate medication use by the elderly - An update [J].
Beers, MH .
ARCHIVES OF INTERNAL MEDICINE, 1997, 157 (14) :1531-1536
[5]  
Boustani M., 2008, Aging Health, V4, P311, DOI [DOI 10.2217/1745509X.4.3.311, 10.2217/1745509XA3.311, 10.2217/1745509X.4.3.311]
[6]   The anticholinergic drug scale as a measure of drug-related anticholinergic burden: Associations with serum anticholinergic activity [J].
Carnahan, Ryan M. ;
Lund, Brian C. ;
Perry, Paul J. ;
Pollock, Bruce G. ;
Culp, Kennith R. .
JOURNAL OF CLINICAL PHARMACOLOGY, 2006, 46 (12) :1481-1486
[7]   Use of the beers criteria to predict adverse drug reactions among first-visit elderly outpatients [J].
Chang, CM ;
Liu, PYY ;
Yang, YHK ;
Yang, YC ;
Wu, CF ;
Lu, FH .
PHARMACOTHERAPY, 2005, 25 (06) :831-838
[8]   Fighting Against Age Discrimination in Clinical Trials [J].
Cherubini, Antonio ;
Del Signore, Susanna ;
Ouslander, Joe ;
Semla, Todd ;
Michel, Jean-Pierre .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2010, 58 (09) :1791-1796
[9]   Inappropriate Medication Use as a Risk Factor for Self-Reported Adverse Drug Effects in Older Adults [J].
Chrischilles, Elizabeth A. ;
VanGilder, Rachel ;
Wright, Kara ;
Kelly, Michael ;
Wallace, Robert B. .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2009, 57 (06) :1000-1006
[10]   Inappropriate prescribing for elderly Americans in a large outpatient population [J].
Curtis, LH ;
Ostbye, T ;
Sendersky, V ;
Hutchison, S ;
Dans, PE ;
Wright, A ;
Woosley, RL ;
Schulman, KA .
ARCHIVES OF INTERNAL MEDICINE, 2004, 164 (15) :1621-1625