Clinical Syndromes: Parkinsonian Gait

被引:66
作者
Ebersbach, Georg [1 ]
Moreau, Caroline [2 ]
Gandor, Florin [1 ]
Defebvre, Luc [2 ]
Devos, David [3 ]
机构
[1] Movement Disorders Clin, Beelitz, Germany
[2] Univ Lille, Serv Neurol & Pathol Mouvement, Pole Neurosci & Appareil Locomoteur CHRU, EA 1046 4559, Lille, France
[3] Univ Lille Nord France, EA 1046 4559, CHRU, Fac Med, Lille, France
关键词
gait; Parkinson's disease; falls; atypical Parkinsonism; DEEP-BRAIN-STIMULATION; PROGRESSIVE SUPRANUCLEAR PALSY; MULTIPLE SYSTEM ATROPHY; PEDUNCULOPONTINE NUCLEUS; SUBTHALAMIC NUCLEUS; POSTURAL INSTABILITY; SYDNEY MULTICENTER; CONTROLLED-TRIAL; NATURAL-HISTORY; BASAL GANGLIA;
D O I
10.1002/mds.25675
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Disturbances of gait manifest in almost all cases of Parkinson's disease (PD), often leading to loss of mobility and increased mortality. In this review a clinically oriented approach to gait disorders in different stages of PD is presented. In addition, interactions between motor behavior and mental processing will be discussed. Analyzing the clinical features of gait can be helpful to differentiate PD from atypical forms of parkinsonism. Bedside tests to distinguish parkinsonian gait disorders are reviewed. There is still an unmet need to effectively treat complex gait disturbances, which are frequently not responsive to dopamine replacement medication. We thus present current approaches for the management of dopa-refractory gait disorders. (c) 2013 International Parkinson and Movement Disorder Society
引用
收藏
页码:1552 / 1559
页数:8
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