Signaling phosphate starvation

被引：157

作者：

Lenburg, ME

OShea, EK

机构：

[1] Dept. of Biochemistry and Biophysics, School of Medicine, Univ. of California at S. Francisco, San Francisco

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1996年 / 21卷 / 10期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0968-0004(96)10048-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Phosphate starvation induces the transcription of several genes involved in phosphate metabolism in the budding yeast Saccharomyces cerevisiae. The signal transduction pathway that mediates this response consists of components that resemble those used to regulate the eukaryotic cell cycle; these include a cyclin-dependent kinase or CDK (Pho85), a cyclin (Pho80) and a CDK inhibitor (Pho81). The possibility that this pathway mediates cell-cycle responses to phosphate starvation is discussed.

引用

页码：383 / 387

页数：5

共 42 条

[1] STUDIES ON THE STRUCTURE, EXPRESSION AND FUNCTION OF THE YEAST REGULATORY GENE PHO2 [J].

BERBEN, G ;

LEGRAIN, M ;

HILGER, F .

GENE, 1988, 66 (02) :307-312

[2] EXPRESSION AND PURIFICATION OF THE HIGH-AFFINITY PHOSPHATE TRANSPORTER OF SACCHAROMYCES-CEREVISIAE [J].

BERHE, A ;

FRISTEDT, U ;

PERSSON, BL .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1995, 227 (1-2) :566-572

[3] PHYSIOLOGICAL CONTROL OF REPRESSIBLE ACID-PHOSPHATASE GENE TRANSCRIPTS IN SACCHAROMYCES-CEREVISIAE [J].

BOSTIAN, KA ;

LEMIRE, JM ;

HALVORSON, HO .

MOLECULAR AND CELLULAR BIOLOGY, 1983, 3 (05) :839-853

[4] INVITRO SYNTHESIS OF REPRESSIBLE YEAST ACID-PHOSPHATASE - IDENTIFICATION OF MULTIPLE MESSENGER-RNAS AND PRODUCTS [J].

BOSTIAN, KA ;

LEMIRE, JM ;

CANNON, LE ;

HALVORSON, HO .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1980, 77 (08) :4504-4508

[5] THE PHO84 GENE OF SACCHAROMYCES-CEREVISIAE ENCODES AN INORGANIC-PHOSPHATE TRANSPORTER [J].

BUNYA, M ;

NISHIMURA, M ;

HARASHIMA, S ;

OSHIMA, Y .

MOLECULAR AND CELLULAR BIOLOGY, 1991, 11 (06) :3229-3238

[6] Two new genes, PHO86 and PHO87, involved in inorganic phosphate uptake in Saccharomyces cerevisiae [J].

BunYa, M ;

Shikata, K ;

Nakade, S ;

Yompakdee, C ;

Harashima, S ;

Oshima, Y .

CURRENT GENETICS, 1996, 29 (04) :344-351

[7] MOLECULAR ANALYSIS OF THE PHO81 GENE OF SACCHAROMYCES-CEREVISIAE [J].

CREASY, CL ;

MADDEN, SL ;

BERGMAN, LW .

NUCLEIC ACIDS RESEARCH, 1993, 21 (08) :1975-1982

[8] COREGULATION OF PURINE AND HISTIDINE BIOSYNTHESIS BY THE TRANSCRIPTIONAL ACTIVATORS BAS1 AND BAS2 [J].

DAIGNANFORNIER, B ;

FINK, GR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (15) :6746-6750

[9] CELL-CYCLE CONTROL BY A COMPLEX OF THE CYCLIN HCS26 (PCL1) AND THE KINASE PHO85 [J].

ESPINOZA, FH ;

OGAS, J ;

HERSKOWITZ, I ;

MORGAN, DO .

SCIENCE, 1994, 266 (5189) :1388-1391

[10] POSITIVE AND NEGATIVE REGULATORS OF THE SACCHAROMYCES-CEREVISIAE PHO SYSTEM PARTICIPATE IN SEVERAL CELL FUNCTIONS [J].

GILLIQUET, V ;

BERBEN, G .

FEMS MICROBIOLOGY LETTERS, 1993, 108 (03) :333-339

← 1 2 3 4 5 →