Treatment of grade 3 anal intraepithelial neoplasia by complete anal mucosal excision without fecal diversion - Report of a case

被引：13

作者：

Lyons, M

Francis, N

Allen-Mersh, TG

机构：

[1] Chelsea & Westminster Hosp, Imperial Coll, Sch Med, Dept Gastrointestinal Surg, London, England

[2] Chelsea & Westminster Hosp, Imperial Coll, Sch Med, Dept Pathol, London, England

来源：

DISEASES OF THE COLON & RECTUM | 1999年 / 42卷 / 10期

关键词：

AIN; 3; anal neoplasia; treatment; mucosal excision;

D O I：

10.1007/BF02234227

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

PURPOSE: The aim of this study was to remove completely the risk of malignant transformation without permanent or temporary fecal diversion in a patient with extensive anal intraepithelial neoplasia. METHODS: ALL anal canal mucosa and the lowest 1.5 cm of rectal mucosa were excised and the adjacent rectal mucosa and submucosa advanced to the anal verge skin. RESULTS: The patient achieved normal continence within a month after the operation. Multiple anal canal biopsies at 12 months after the operation revealed normal rectal mucosa. CONCLUSIONS: Total anal mucosal excision offers a relatively simple means of removing the malignant risk of anal intraepithelial neoplasia without fecal diversion in selected patients.

引用

页码：1342 / 1344

页数：3

共 10 条

[1] RELATION OF SENSATION IN ANAL CANAL TO FUNCTIONAL ANAL SPHINCTER - A POSSIBLE FACTOR IN ANAL CONTINENCE [J].