High-dose chemotherapy with autologous stem cell rescue for brain tumors

被引：30

作者：

Dunkel, IJ

Finlay, JL

机构：

[1] Mem Sloan Kettering Canc Ctr, Dept Pediat, New York, NY 10021 USA

[2] NYU, Med Ctr, New York, NY 10016 USA

来源：

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY | 2002年 / 41卷 / 02期

关键词：

high-grade astrocytoma; ependymoma; oligodendroglioma; brain stem tumor; medulloblastoma; PNET (primitive neuroectodermal tumor); germ cell tumor; hematopoietic stem cell transplantation; chemotherapy;

D O I：

10.1016/S1040-8428(01)00156-1

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The use of high-dose chemotherapy with stem cell rescue for malignant brain tumors is reviewed. Promising results have been reported in patients with medulloblastomas, supratentorial PNET's and high-grade astrocytomas. Results thus far have been disappointing for ependymomas and brain stem gliomas. The role of this treatment strategy for other chemotherapy-sensitive tumors such as oligodendrogliomas and central nervous system germ cell tumors has yet to be determined. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：197 / 204

页数：8

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