Self-appraisal decisions evoke dissociated dorsal-ventral aMPFC networks

被引:87
作者
Schmitz, TW
Johnson, SC
机构
[1] William S Middleton Mem Vet Hosp 11G, Madison, WI 53705 USA
[2] Univ Wisconsin, Madison, WI 53706 USA
关键词
D O I
10.1016/j.neuroimage.2005.10.030
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The anterior medial prefrontal cortex (aMPFC) is consistently active during personally salient decisions, yet the differential contributor), processes of this region along the dorsal-ventral axis are less understood. Using a self-appraisal decision-making task and functional magnetic resonance imaging, we demonstrated task-dependent connectivity of ventral aMPFC with amygdala, insula, and nucleus accumbens, and dorsal aMPFC connectivity with dorsolateral PFC and bilateral hippocampus. These aMPFC networks appear to subserve distinct contributory processes inherent to self-appraisal decisions, specifically a dorsally mediated cognitive and a ventrally mediated affective/self-relevance network. (c) 2005 Elsevier Inc. All rights reserved.
引用
收藏
页码:1050 / 1058
页数:9
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