Renal vitamin D receptor expression and vitamin D renoprotection

被引:12
作者
Dusso, Adriana S. [1 ]
机构
[1] Univ Lleida, Lleida Sch Med, Lleida Inst Biomed Res, Div Expt Nephrol,IRBLleida, Lleida 25198, Spain
关键词
KIDNEY;
D O I
10.1038/ki.2012.30
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
100201 [内科学]; 100221 [泌尿外科学];
摘要
Therapy to enhance the renoprotective actions of vitamin D receptor (VDR) activation should safely overcome the distinct VDR content along the nephron to effectively control renal calcium reabsorption, control renal klotho levels for the phosphaturic actions of FGF23, and inhibit proteinuria and the activation of the renin-angiotensin system. Kidney International (2012) 81, 937-939. doi: 10.1038/ki.2012.30
引用
收藏
页码:937 / 939
页数:3
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