biomaterial;
bone chips dehydrated with solvent;
graft;
bone healing;
D O I:
10.1177/147323000203000209
中图分类号:
R-3 [医学研究方法];
R3 [基础医学];
学科分类号:
1001 [基础医学];
摘要:
The effect of bone chips dehydrated with solvent on the healing of bone defects was evaluated. Solvent-dehydrated spongiose bone chips were placed in experimentally formed cavities in the right back tibia of rabbits. After 10, 20 and 30 days, histopathological cross-sections from the bone grafts were examined microscopically for bone healing and formation of spongiose bone, cortex and bone marrow. Spongiose bone chips had a positive and accelerating influence on the healing of bone defects in the 10-day period after transplantation, but no significant differences were observed between the treated and control groups 20 and 30 days after transplantation.