One-pot asymmetric autocatalytic reaction with remarkable amplification of enantiomeric excess

被引：61

作者：

Shibata, T ^{[1
]}

Hayase, T ^{[1
]}

Yamamoto, J ^{[1
]}

Soai, K ^{[1
]}

机构：

[1] SCI UNIV TOKYO,FAC SCI,DEPT APPL CHEM,SHINJUKU KU,TOKYO 162,JAPAN

来源：

TETRAHEDRON-ASYMMETRY | 1997年 / 8卷 / 11期

关键词：

D O I：

10.1016/S0957-4166(97)00183-3

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A trace amount (ca. 3 mg) of 2-methylpyrimidyl alkanol with only a slight enantiomeric excess (0.2-0.3% e.e.) was auto-multiplied with dramatic amplification of enantiomeric excess (up to ca. 90% e.e.) in one-pot asymmetric autocatalytic reaction using diisopropylzinc and 2-methylpyrimidine-5-carbaldehyde. (C) 1997 Elsevier Science Ltd.

引用

页码：1717 / 1719

页数：3

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