Adrenomedullin - An autocrine/paracrine factor for cardiorenal protection

被引：34

作者：

Tsuruda, T ^{[1
]}

Burnett, JC ^{[1
]}

机构：

[1] Mayo Clin & Mayo Fdn, Cardiorenal Res Lab, Rochester, MN 55905 USA

来源：

CIRCULATION RESEARCH | 2002年 / 90卷 / 06期

关键词：

adrenomedullin; transgenic; knockout; autocrine; paracrine;

D O I：

10.1161/01.RES.0000015462.11528.28

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

In summary, the study by Nishimatsu and coworkers advances our understanding of the biology of endogenous AM and supports the role of endogenous AM as an autocrine or paracrine factor in cardiorenal regulation. Furthermore, endogenous AM contributes a cytoprotective effect against organ damage, indicating that AM is a potential therapeutic candidate for the treatment of cardiovascular and renal disease.

引用

页码：625 / 627

页数：3

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