Synthesis and evaluation of a chiral heterogeneous transfer hydrogenation catalyst

被引：100

作者：

Bayston, DJ ^{[1
]}

Travers, CB ^{[1
]}

Polywka, MEC ^{[1
]}

机构：

[1] Oxford Asymmetry Int Ltd, Abingdon OX14 4SD, Oxon, England

来源：

TETRAHEDRON-ASYMMETRY | 1998年 / 9卷 / 12期

关键词：

D O I：

10.1016/S0957-4166(98)00214-6

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A polymer bound transfer hydrogenation catalyst has been developed based on Noyori's (1S,2S)- or (1R,2R)-N-(p-tolylsulfonyl)-1,2-diphenylethylenediamine. The ruthenium catalysed reduction of acetophenone was examined and the activity of the catalyst was found to be dependent on the type of polymer used. The catalyst was found to be reusable and retained high ee's when HCO2H:Et3N was used as the hydrogen donor. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：2015 / 2018

页数：4

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