Predictors of persistent ADHD: An 11-year follow-up study

被引:252
作者
Biederman, Joseph [1 ,2 ]
Petty, Carter R. [1 ,2 ]
Clarke, Allison [1 ,2 ]
Lomedico, Alexandra [1 ,2 ]
Faraone, Stephen V. [3 ,4 ]
机构
[1] Massachusetts Gen Hosp, Dept Psychiat, Boston, MA 02114 USA
[2] Harvard Univ, Sch Med, Boston, MA 02114 USA
[3] SUNY Upstate Med Univ, Dept Psychiat, Syracuse, NY 13210 USA
[4] SUNY Upstate Med Univ, Dept Neurosci & Physiol, Syracuse, NY 13210 USA
基金
美国国家卫生研究院;
关键词
ADHD; Persistence; Predictors; Longitudinal; Young adult; ATTENTION-DEFICIT HYPERACTIVITY; AGE-DEPENDENT DECLINE; DEFICIT/HYPERACTIVITY DISORDER; RISK-FACTORS; BOYS; COMORBIDITY; CHILDHOOD; CHILDREN; ADOLESCENCE; DEFINITION;
D O I
10.1016/j.jpsychires.2010.06.009
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Objective: Despite the existence of several follow-up studies of children with ADHD followed up into adulthood, there is limited information on whether patterns of persistence and remission in ADHD can be predicted over the long term. The main aim of this study was to evaluate predictors of persistence of ADHD in a large sample of boys with and without ADHD followed prospectively for 11 years into young adulthood. Method: Subjects were Caucasian, non-Hispanic boys with (N = 110) and without (N = 105) ADHD who were 6-17 years old at the baseline assessment (mean age 11 years) and 15 to 31 years old at the follow-up assessment (mean age 22 years). Subjects were comprehensively and blindly assessed with structured diagnostic interviews and assessments of cognitive, social, school, and family functioning. Results: At the 11-year follow-up, 78% of children with ADHD continued to have a full (35%) or a partial persistence (subsyndromal (22%), impaired functioning (15%), or remitted but treated (6%)). Predictors of persistence were severe impairment of ADHD, psychiatric comorbidity, and exposure to maternal psychopathology at baseline. Conclusions: These findings prospectively confirm that persistence of ADHD over the long term is predictable from psychosocial adversity and psychiatric comorbidity ascertained 11 years earlier. (C) 2010 Elsevier Ltd. All rights reserved.
引用
收藏
页码:150 / 155
页数:6
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