Short echo time MRI enables visualisation of the natural state of human stratum corneum water in vivo

被引:19
作者
Ablett, S [1 ]
Burdett, NG [1 ]
Carpenter, TA [1 ]
Hall, LD [1 ]
Salter, DC [1 ]
机构
[1] UNIV CAMBRIDGE,SCH CLIN MED,HERCHEL SMITH LAB MED CHEM,CAMBRIDGE CB2 2PZ,ENGLAND
关键词
magnetic resonance imaging; skin hydration; skin imaging; stratum corneum;
D O I
10.1016/0730-725X(95)02105-3
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 [临床医学]; 100207 [影像医学与核医学]; 1009 [特种医学];
摘要
High resolution magnetic resonance imaging studies on skin have been limited by their inability to detect the low-moisture-content outer layers near the surface of the stratum corneum, The hydration of these outer layers is especially important physiologically. The present study shows that by using a short echo time of 5 ms it becomes possible to observe these layers in all but a few individuals with exceptionally dry skin, The quality of the images can be further improved by the use of separate transmit and receive coils, which reduces the rapid fall-off in signal intensity encountered with a single surface coil used both to transmit and receive.
引用
收藏
页码:357 / 360
页数:4
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