Microreactor technology: A revolution for the fine chemical and pharmaceutical industries?

被引：467

作者：

Roberge, DM ^{[1
]}

Ducry, L ^{[1
]}

Bieler, N ^{[1
]}

Cretton, P ^{[1
]}

Zimmermann, B ^{[1
]}

机构：

[1] Lonza Ltd, CH-3930 Visp, Switzerland

来源：

CHEMICAL ENGINEERING & TECHNOLOGY | 2005年 / 28卷 / 03期

关键词：

D O I：

10.1002/ceat.200407128

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

50% of reactions in the fine chemical/pharmaceutical industry could benefit from a continuous process based mainly on microreactor technology. However, the frequent presence of a solid phase still hinders the widespread application of such a technology as a multi-purpose solution. For small scale and pilot productions, speed in process R&D, as well as the avoidance of scale-up issues, are the main drivers. On the other hand, for large scale productions, a gain in yield and safety are the main motivations for the use of micoreactor technology. The gain in yield must be significant in order to cope with the increase in capital expenditure associated with the development of a new technology.

引用

页码：318 / 323

页数：6

共 11 条

[1]

Ainsworth D, 2003, CHEM ENG-NEW YORK, V110, P42

[2] Analysis and improvement of strong exothermic nitrations in microreactors [J].