Pneumonia in older persons

被引:62
作者
Loeb, M
机构
[1] McMaster Univ, Dept Pathol, Hamilton, ON, Canada
[2] McMaster Univ, Dept Mol Med, Hamilton, ON, Canada
[3] McMaster Univ, Dept Clin Epidemiol & Biostat, Hamilton, ON, Canada
基金
加拿大健康研究院;
关键词
D O I
10.1086/379076
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Community-acquired pneumonia (CAP) is an important threat to the health of older adults. Streptococcus pneumonia remains the most important cause of CAP. Risk factors for CAP include alcoholism, asthma, immunosuppression, chronic respiratory or cardiac disease, institutionalization, and increasing age. Residents of long-term care facilities-a distinct subpopulation of elderly people-are at particularly high risk for developing pneumonia. In this setting, swallowing difficulties, witnessed aspiration, and receipt of sedatives are potentially modifiable risk factors. The clinical presentation in elderly patients is characterized by a reduced prevalence of nonrespiratory symptoms. Few randomized, controlled trials of therapy exist for elderly persons living in the community or in a long-term care setting. Good evidence exists to support the annual administration of influenza vaccine to older adults. Although evidence in clinical trials differs from evidence in observational studies that demonstrate clear benefits associated with the polysaccharide pneumococcal vaccine in this population, the vaccine is recommended for adults aged.
引用
收藏
页码:1335 / 1339
页数:5
相关论文
共 31 条
[1]  
[Anonymous], 1995, MMWR MORB MORTAL WKL, V44, P535
[2]   Effects of influenza vaccination of health-care workers on mortality of elderly people in long-term care: a randomised controlled trial [J].
Carman, WF ;
Elder, AG ;
Wallace, LA ;
McAulay, K ;
Walker, A ;
Murray, GD ;
Stott, DJ .
LANCET, 2000, 355 (9198) :93-97
[3]   A prognostic rule for elderly patients admitted with community-acquired pneumonia [J].
Conte, HA ;
Chen, YT ;
Mehal, W ;
Scinto, JD ;
Quagliarello, VJ .
AMERICAN JOURNAL OF MEDICINE, 1999, 106 (01) :20-28
[4]   Efficacy of pneumococcal polysaccharide vaccine in immunocompetent adults:: a meta-analysis of randomized trials [J].
Cornu, C ;
Yzèbe, D ;
Léophonte, P ;
Gaillat, J ;
Boissel, JP ;
Cucherat, M .
VACCINE, 2001, 19 (32) :4780-4790
[5]   Risk factors for community-acquired pneumonia diagnosed by general practitioners in the community [J].
Farr, BM ;
Woodhead, MA ;
Macfarlane, JT ;
Bartlett, CLR ;
McCracken, JS ;
Wadsworth, J ;
Miller, DL .
RESPIRATORY MEDICINE, 2000, 94 (05) :422-427
[6]   A prediction rule to identify low-risk patients with community-acquired pneumonia [J].
Fine, MJ ;
Auble, TE ;
Yealy, DM ;
Hanusa, BH ;
Weissfeld, LA ;
Singer, DE ;
Coley, CM ;
Marrie, TJ ;
Kapoor, WN .
NEW ENGLAND JOURNAL OF MEDICINE, 1997, 336 (04) :243-250
[7]   Medical outcomes and antimicrobial costs with the use of the American Thoracic Society guidelines for outpatients with community-acquired pneumonia [J].
Gleason, PP ;
Kapoor, WN ;
Stone, RA ;
Lave, JR ;
Obrosky, DS ;
Schulz, R ;
Singer, DE ;
Coley, CM ;
Marrie, TJ ;
Fine, MJ .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1997, 278 (01) :32-39
[8]   Associations between initial antimicrobial therapy and medical outcomes for hospitalized elderly patients with pneumonia [J].
Gleason, PP ;
Meehan, TP ;
Fine, JM ;
Galusha, DH ;
Fine, MJ .
ARCHIVES OF INTERNAL MEDICINE, 1999, 159 (21) :2562-2572
[9]   THE EFFICACY OF INFLUENZA VACCINE IN ELDERLY PERSONS - A METAANALYSIS AND REVIEW OF THE LITERATURE [J].
GROSS, PA ;
HERMOGENES, AW ;
SACKS, HS ;
LAU, J ;
LEVANDOWSKI, RA .
ANNALS OF INTERNAL MEDICINE, 1995, 123 (07) :518-527
[10]   Effectiveness of pneumococcal polysaccharide vaccine in older adults [J].
Jackson, LA ;
Neuzil, KM ;
Yu, OC ;
Benson, P ;
Barlow, WE ;
Adams, AL ;
Hanson, CA ;
Mahoney, LD ;
Shay, DK ;
Thompson, WW .
NEW ENGLAND JOURNAL OF MEDICINE, 2003, 348 (18) :1747-1755