Update on National Toxicology Program (NTP) assays with genetically altered or "transgenic" mice

被引：15

作者：

Bucher, JR ^{[1
]}

机构：

[1] NIEHS, Res Triangle Pk, NC 27709 USA

来源：

ENVIRONMENTAL HEALTH PERSPECTIVES | 1998年 / 106卷 / 10期

关键词：

alternative; cancer assays; genetically altered mice; transgenic mice; NTP Board of Scientific Counselors review;

D O I：

10.2307/3434087

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

The NTP is evaluating several lines of genetically altered mice for possible use in identifying and assessing carcinogens. The NIEHS/NTP programs and progress in this area were recently reviewed by the NTP Board of Scientific Counselors (BSC). A number of comments and concerns were raised. This commentary summarizes and responds to the BSC review and offers some thoughts on future directions for this line of research as well as possible ways genetically altered mice might be integrated into a comprehensive testing strategy.

引用

页码：619 / 621

页数：3

共 6 条

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