Rational design of a fluorescence-turn-on sensor array for phosphates in blood serum

被引：181

作者：

Zyryanov, Grigory V. ^{[1
]}

Palacios, Manuel A. ^{[1
]}

Anzenbacher, Pavel, Jr. ^{[1
]}

机构：

[1] Bowling Green State Univ, Ctr Photochem Sci, Dept Chem, Bowling Green, OH 43403 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2007年 / 46卷 / 41期

关键词：

analytical methods; anions; host-guest systems; sensors; supramolecular chemistry;

D O I：

10.1002/anie.200702611

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Getting turned on: An order-of-magnitude fluorescence amplification of simple tripodal sensors has been observed in the presence of phosphate ions. An X-ray structure analysis of one of the complexes (see picture) shows the binding of three phosphate ions, which closely resembles the anionic part of ATP, by the sensor. The sensors were used to generate cross-reactive arrays that can detect anions in human serum. (Figure Presented). © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：7849 / 7852

页数：4

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