Inverse planning with constraints to generate smoothed intensity-modulated beams

被引:73
作者
Webb, S
Convery, DJ
Evans, PM
机构
[1] Inst Canc Res, Joint Dept Phys, Sutton SM2 5PT, Surrey, England
[2] Royal Marsden NHS Trust, Sutton SM2 5PT, Surrey, England
关键词
D O I
10.1088/0031-9155/43/10/008
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Highly conformal dose distributions can be generated by intensity-modulated radiotherapy. Intensity-modulated beams (IMBs) are generally determined by inverse-planning techniques designed to maximize conformality. Usually such techniques apply no constraints on the form of the IMBs which may then develop fine-scale modulation. In this paper we present a technique for generating smoother IMBs, which yields a dose distribution almost identical to that without the constraint on the form of the IMBs. The method applies various filters successively at intervals throughout the iterative inverse planning. It is shown that the IMBs so determined using a simple median window filter have desirable properties in terms of increasing the efficiency of delivery by the dynamic multileaf collimator method and may be 'more like conventional beams' than unconstrained, highly modulated IMBs.
引用
收藏
页码:2785 / 2794
页数:10
相关论文
共 18 条
[1]  
Bortfeld T, 1997, PROCEEDINGS OF THE XIITH INTERNATIONAL CONFERENCE ON THE USE OF COMPUTERS IN RADIATION THERAPY, P1
[2]   Modulated beam conformal therapy for head and neck tumors [J].
Boyer, AL ;
Geis, P ;
Grant, W ;
Carol, M .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1997, 39 (01) :227-236
[3]  
BRAHME A, 1995, RAD THERAPY PHYSICS, P209
[4]  
Carol MP, 1997, PROCEEDINGS OF THE XIITH INTERNATIONAL CONFERENCE ON THE USE OF COMPUTERS IN RADIATION THERAPY, P317
[5]  
CONVERY D, 1998, P EL ONC SYST 1 US C, P50
[6]   Generation of discrete beam-intensity modulation by dynamic multileaf collimation under minimum leaf separation constraints [J].
Convery, DJ ;
Webb, S .
PHYSICS IN MEDICINE AND BIOLOGY, 1998, 43 (09) :2521-2538
[7]  
GUSTAFSSON A, 1998, MED BIOL ENG COM S 2, V35, P918
[8]   AN ALGORITHM FOR MAXIMIZING THE PROBABILITY OF COMPLICATION-FREE TUMOR-CONTROL IN RADIATION-THERAPY [J].
KALLMAN, P ;
LIND, BK ;
BRAHME, A .
PHYSICS IN MEDICINE AND BIOLOGY, 1992, 37 (04) :871-890
[9]  
LEACH MO, 1983, INFORMATION PROCESSI, P151
[10]  
Preiser K, 1997, PROCEEDINGS OF THE XIITH INTERNATIONAL CONFERENCE ON THE USE OF COMPUTERS IN RADIATION THERAPY, P425