A mechanistic study on the effect of ethanol and importance of water on permeation of drugs through human third-degree burn eschar

被引：7

作者：

Ghaffari, Azadeh ^{[1
]}

Moghimi, Hamid R. ^{[1
]}

Manafi, Ali ^{[2
]}

Hosseini, Habibolah ^{[3
]}

机构：

[1] Shaheed Beheshti Univ Med Sci, Dept Pharmaceut, Sch Pharm, Tehran, Iran

[2] Univ Tehran Med Sci, Sch Med, Dept Surg, Tehran, Iran

[3] Shaheed Sadooghi Univ Med Sci, Sch Med, Dept Anesthesia & Intens Care, Yazd, Iran

来源：

INTERNATIONAL WOUND JOURNAL | 2012年 / 9卷 / 02期

关键词：

Burn eschar; Drug permeation; Ethanol; Hydration; Thermal analysis; SKIN PERMEABILITY; ABSORPTION; MEMBRANES; VEHICLE; EXTRACT; LIPIDS;

D O I：

10.1111/j.1742-481X.2011.00879.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100227 [皮肤病学];

摘要：

Ethanol that affects hydration of skin and used in wound treatment formulations was studied here for its effect on permeation of drugs through burn eschar and to investigate the presence of a porous pathway in this barrier.

引用

页码：221 / 229

页数：9

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